Condition Skull Base Care

Epidermoid and Dermoid Tumor

Benign, slow-growing tumors that develop from cells trapped during early development and may grow around nerves and blood vessels near the skull base.

Medically reviewed by Fabio A. Frisoli, MD Last reviewed January 2, 2026 5 min read

Quick Answer

Epidermoid and dermoid tumors are rare, benign growths that develop from cells trapped during early development. They often grow slowly and may remain unnoticed for years. Epidermoid tumors in particular can grow around nerves and blood vessels near the skull base, sometimes causing symptoms as they press on nearby structures. When treatment is needed, surgery aims to remove as much of the growth as safely possible while protecting surrounding nerves, blood vessels, and other critical structures.

Key Takeaways

  • Epidermoid and dermoid tumors are rare, benign growths that develop from cells trapped during early development.
  • They grow slowly and may not cause symptoms for many years.
  • Epidermoid tumors can grow around nerves and blood vessels, particularly near the skull base.
  • Symptoms depend on location and may include facial pain, hearing or balance problems, headaches, numbness, or weakness.
  • When treatment is needed, surgery aims to remove as much of the growth as safely possible.
  • Long-term imaging may be recommended because residual or recurrent growth can occur.

At a Glance

What it isA rare, benign developmental growth
GrowthUsually slow-growing
Common locationsSkull base and areas around the brainstem
Possible symptomsFacial pain or numbness, hearing or balance problems, headaches, or weakness
DiagnosisMRI with specialized sequences
TreatmentObservation or surgical removal, depending on symptoms, growth, and location
Long-term careFollow-up imaging when appropriate

Symptoms

Because these tumors grow slowly and mold around nearby structures, symptoms develop gradually and depend on location. Tumors near the cranial nerves can cause facial pain, facial numbness or weakness, hearing changes, or balance problems. Some can cause headaches, and occasionally they irritate nearby structures enough to cause symptoms such as trigeminal neuralgia.

Many are discovered when symptoms prompt imaging, or incidentally. Their tendency to insinuate between nerves and vessels is characteristic and influences how they are treated.

Common Warning Signs

  • Gradual facial pain or numbness
  • Hearing changes or balance problems
  • Headaches
  • Facial weakness
  • Symptoms resembling trigeminal neuralgia

When to Seek Care Promptly

  • Rapidly worsening neurological symptoms
  • New facial weakness
  • Severe headache with fever (possible inflammation)
  • Sudden hearing loss
  • New difficulty swallowing or double vision

Diagnosis

MRI with specialized sequences is the key study, because epidermoid tumors have a characteristic appearance that specific MRI techniques can highlight, helping distinguish them from other cysts and tumors. The imaging shows how the tumor relates to and surrounds nearby nerves and vessels.

Defining this relationship is essential for surgical planning, since the tumor often extends into crevices around critical structures. A definitive diagnosis is confirmed when the tumor is examined after removal.

Treatment

Treatment depends on the type, size, location, symptoms, and relationship of the tumor to nearby nerves and blood vessels. Small or incidentally discovered tumors that are not causing symptoms may sometimes be monitored with periodic imaging.

When surgery is recommended, the goal is to remove as much of the tumor as safely possible while protecting surrounding nerves, blood vessels, and other critical structures. Because epidermoid tumors in particular can grow around or adhere to these structures, complete removal may not always be safe.

If a portion of the tumor is intentionally left behind to protect a critical nerve or blood vessel, long-term imaging may be used to monitor for regrowth. At Atlantic Brain and Spine, these cases are managed by the skull base team using microsurgical and, when appropriate, endoscopic techniques.

The Diagnosis-to-Treatment Pathway

1. Evaluation

History and neurological examination assess symptoms and possible cranial nerve involvement.

2. Specialized MRI

MRI helps identify the tumor, determine its extent, and evaluate its relationship to nearby structures.

3. Treatment planning

Symptoms, growth, location, and involvement of nearby nerves and blood vessels help determine whether observation or surgery is appropriate.

4. Observation when appropriate

Tumors that are not causing significant symptoms or concerning changes may be monitored with periodic imaging.

5. Surgical planning

When surgery is recommended, the safest approach is selected based on the tumor's location and relationship to critical structures.

6. Surgical removal

Surgery aims to remove as much of the tumor as safely possible while protecting neurological function.

7. Follow-up

Imaging monitors for residual or recurrent growth over time when appropriate.

Frequently Asked Questions

They are benign, slow-growing tumors that form from cells trapped during early development. Epidermoid tumors contain skin-like cellular material, and dermoid tumors can also contain elements such as hair or glands. Both tend to occur at the skull base and grow slowly around nearby structures.

No, they are benign. Their challenge comes not from aggressive growth but from their tendency to wrap around and adhere to critical nerves and blood vessels, which can make complete surgical removal difficult and can cause symptoms as they enlarge.

Treatment depends on the tumor’s size, location, symptoms, and relationship to nearby nerves and blood vessels. Tumors that are not causing significant symptoms may sometimes be monitored with periodic imaging. When surgery is recommended, the goal is to remove as much of the tumor as safely possible while protecting surrounding nerves and blood vessels. Because these tumors can grow around or adhere to critical structures, a small portion may sometimes be left behind to protect neurological function.

These tumors tend to insinuate into the crevices around nerves and blood vessels and adhere to them. Removing every bit without injuring those structures is not always safe, so a small amount may be left behind. Because they grow slowly, residual tumor can be monitored and treated later if needed.

Yes. When located near the trigeminal nerve, these tumors can cause facial pain, sometimes resembling trigeminal neuralgia, as well as facial numbness. Tumors near other cranial nerves can cause hearing, balance, or facial movement symptoms, depending on their location.

When completely removed, recurrence is uncommon. When a portion is left to protect critical structures, it typically regrows slowly, and further surgery can be done later if it becomes symptomatic. Follow-up imaging monitors for any regrowth over time.

Specialists Who Treat Epidermoid and Dermoid Tumors

Your care is provided by Atlantic Brain and Spine’s experienced skull base specialists.

Fabio A. Frisoli, MD
Fabio A. Frisoli, MD
Neurosurgery
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Stephen A. Johnson, MD
Stephen A. Johnson, MD
Neurosurgery
View profile
Yaron A. Moshel, MD, PhD
Yaron A. Moshel, MD, PhD
Neurosurgery
View profile

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